LC3 fluorescent puncta in autophagosomes or in protein aggregates can be distinguished by FRAP analysis in living cells
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چکیده
منابع مشابه
Nuclear LC3-positive puncta in stressed cells do not represent autophagosomes.
This letter points out an important potential artifact when using immunolabeling techniques with confocal microscopy to identify autophagosomes. Our laboratory has been investigating autophagy induced by varicella-zoster virus (VZV), a human herpesvirus. Although closely related to herpes simplex virus type 1 (HSV-1), VZV lacks the inhibitors of autophagy harbored within the HSV genome (1), (2)...
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ژورنال
عنوان ژورنال: Autophagy
سال: 2013
ISSN: 1554-8627,1554-8635
DOI: 10.4161/auto.23814